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hyfC hydrogenase 4 component C [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947492, updated on 6-May-2021

Summary

Gene symbol
hyfC
Gene description
hydrogenase 4 component C
Primary source
ASAP:ABE-0008183
Locus tag
b2483
See related
ECOCYC:G7300
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2479
Summary
On the basis of sequence similarity to hycBCDEFG, which encodes hydrogenase 3, the ten-gene cluster hyfABCDEFGHIJ was presumed to encode a hydrogenase that interacts with formate dehydrogenase (FdhF) to produce an active formate hydrogenlyase complex. [More information is available at EcoCyc: G7300].
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Genomic context

Sequence:
NC_000913.3 (2603847..2604794)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase 4 component A Neighboring gene hydrogenase 4 component B Neighboring gene hydrogenase 4 component D Neighboring gene hydrogenase 4 component E

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to DNA damage stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2603847..2604794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416978.4 hydrogenase 4 component C [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416978.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P77858
    Conserved Domains (1) summary
    COG0650
    Location:5313
    HyfC; Formate hydrogenlyase subunit 4 [Energy production and conversion]
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