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mutY adenine DNA glycosylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947447, updated on 11-Oct-2018

Summary

Gene symbol
mutY
Gene description
adenine DNA glycosylase
Primary source
EcoGene:EG10627
Locus tag
b2961
See related
ASAP:ABE-0009720; ECOCYC:EG10627
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2956; micA
Summary
MutY serves as an adenine glycosylase mismatch repair enzyme in Escherichia coli which works to correct G-A mispairs to G-C base pairs. [More information is available at EcoCyc: EG10627].

Genomic context

Sequence:
NC_000913.3 (3103013..3104065)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative EcfF Neighboring gene protein YggL Neighboring gene tRNA m(7)G46 methyltransferase Neighboring gene putative Fe(2(+))-trafficking protein Neighboring gene membrane-bound lytic murein transglycosylase C

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Base excision repair, organism-specific biosystem (from KEGG)
    Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
  • Base excision repair, conserved biosystem (from KEGG)
    Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenine/guanine mispair binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
oxidized purine DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
purine-specific mismatch base pair DNA N-glycosylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
base-excision repair IDA
Inferred from Direct Assay
more info
PubMed 
mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
adenine DNA glycosylase
NP_417436.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3103013..3104065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417436.1 adenine DNA glycosylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417436.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P17802
    Conserved Domains (1) summary
    PRK10880
    Location:1350
    PRK10880; adenine DNA glycosylase; Provisional
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