U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gcvH glycine cleavage system H protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947393, updated on 4-Feb-2024

Summary

Gene symbol
gcvH
Gene description
glycine cleavage system H protein
Primary source
ASAP:ABE-0009534
Locus tag
b2904
See related
ECOCYC:EG10371
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2899; gcv
Summary
The H-protein, coded for by the gcvH gene, is a lipoylprotein that is reduced as it shuttles the methylamine group of glycine from the P-protein to the T-protein and is reoxidized by the dihydrolipoamide dehydrogenase. [More information is available at EcoCyc: EG10371].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3049160..3049549, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative oxidoreductase YgfF Neighboring gene glycine decarboxylase Neighboring gene aminomethyltransferase Neighboring gene protein YqfI

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in glycine decarboxylation via glycine cleavage system IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycine decarboxylation via glycine cleavage system IEA
Inferred from Electronic Annotation
more info
 
involved_in glycine decarboxylation via glycine cleavage system NAS
Non-traceable Author Statement
more info
PubMed 
involved_in one-carbon metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
involved_in protein lipoylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of glycine cleavage complex IEA
Inferred from Electronic Annotation
more info
 
part_of glycine cleavage complex NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
glycine cleavage system H protein
NP_417380.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3049160..3049549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417380.1 glycine cleavage system H protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417380.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A192CAT2, A0AA36L013
    Conserved Domains (1) summary
    PRK01202
    Location:1128
    PRK01202; glycine cleavage system protein GcvH