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ubiH 2-octaprenyl-6-methoxyphenol 4-hydroxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947388, updated on 26-Mar-2025
Official Symbol
ubiH
Official Full Name
2-octaprenyl-6-methoxyphenol 4-hydroxylase
Primary source
ECOCYC:EG11324
Locus tag
b2907
See related
ASAP:ABE-0009545
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
acd; ECK2902; visB
Summary
visC, ubiH, ubiF and mhpA are paralogs. [More information is available at EcoGene: EG11324]. ubiH is thought to encode 2-octaprenyl-6-methoxyphenol hydroxylase, one of the aerobic hydroxylases in the ubiquinone biosynthesis pathway. [More information is available at EcoCyc: EG11324].
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Sequence:
NC_000913.3 (3052340..3053518, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YqfI Neighboring gene 2-octaprenylphenol 6-hydroxylase Neighboring gene Xaa-Pro aminopeptidase Neighboring gene PF03695 family protein YgfB Neighboring gene cell division protein ZapA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Pathway for ubiquinone biosynthesis in Escherichia coli K-12: gene-enzyme relationships and intermediates. Young IG, et al. J Bacteriol, 1973 Apr. PMID 4572721, Free PMC Article
  2. Acetaldehyde dehydrogenase activity of the AdhE protein of Escherichia coli is inhibited by intermediates in ubiquinone synthesis. Gupta S, et al. FEMS Microbiol Lett, 2000 Jan 1. PMID 10612730
  3. Isolation and characterization of visible light-sensitive mutants of Escherichia coli K12. Miyamoto K, et al. J Mol Biol, 1991 Jun 5. PMID 2051480
  4. Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone. Nakahigashi K, et al. J Bacteriol, 1992 Nov. PMID 1339425, Free PMC Article
  5. Alternative hydroxylases for the aerobic and anaerobic biosynthesis of ubiquinone in Escherichia coli. Alexander K, et al. Biochemistry, 1978 Oct 31. PMID 365223

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-octaprenyl-6-methoxyphenol hydroxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2-octaprenyl-6-methoxyphenol hydroxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables 2-octaprenyl-6-methoxyphenol hydroxylase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to light stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ubiquinone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquinone biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of ubiquinone biosynthesis complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
2-octaprenyl-6-methoxyphenol 4-hydroxylase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3052340..3053518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417383.1 2-octaprenyl-6-methoxyphenol 4-hydroxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417383.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A895NQJ0, A0A8S7F587
    Conserved Domains (1) summary
    PRK05732
    Location:1 → 392
    PRK05732; 2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
Nucleotide Protein
Heading Accession and Version

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