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mdtI multidrug/spermidine efflux pump membrane subunit MdtI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947333, updated on 6-May-2021

Summary

Gene symbol
mdtI
Gene description
multidrug/spermidine efflux pump membrane subunit MdtI
Primary source
ASAP:ABE-0005343
Locus tag
b1599
See related
ECOCYC:G6857
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1594; ydgE
Summary
MdtI belongs to the SMR efflux pump family, DMT superfamily. [More information is available at EcoGene: EG13926]. MdtI is part of the MdtJI spermidine SMR transporter. [More information is available at EcoCyc: G6857].
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Genomic context

Sequence:
NC_000913.3 (1672820..1673149, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YdgU Neighboring gene putative serine protease YdgD Neighboring gene multidrug/spermidine efflux pump membrane subunit MdtJ Neighboring gene protein YdgV Neighboring gene autoinducer 2 exporter

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables amino-acid betaine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables choline transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables spermidine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables spermidine transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables spermidine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in choline transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycine betaine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermidine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within spermidine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermidine transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within xenobiotic detoxification by transmembrane export across the plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multidrug/spermidine efflux pump membrane subunit MdtI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1672820..1673149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416116.1 multidrug/spermidine efflux pump membrane subunit MdtI [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416116.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69210
    Conserved Domains (1) summary
    PRK10650
    Location:1109
    PRK10650; multidrug/spermidine efflux SMR transporter subunit MdtI
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