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ascG DNA-binding transcriptional repressor AscG [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947305, updated on 6-Jul-2026
Official Symbol
ascG
Official Full Name
DNA-binding transcriptional repressor AscG
Primary source
ECOCYC:EG10087
Locus tag
b2714
See related
ASAP:ABE-0008922
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2709; sac
Summary
The AscG, "arbutin-salicin-cellibiose," transcriptional regulator represses the expression of a cryptic operon (ascFB) whose genes are involved in transport and utilization of the -glucoside sugars arbutin, salicin, and cellibiose. [More information is available at EcoCyc: EG10087].
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Sequence:
NC_000913.3 (2838254..2839264, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene carbamoyl-- Neighboring gene putative electron transport protein HydN Neighboring gene cryptic beta-glucoside specific PTS enzyme IIBC component Neighboring gene cryptic 6-phospho-beta-glucosidase AscB

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Participation of regulator AscG of the beta-glucoside utilization operon in regulation of the propionate catabolism operon. Ishida Y, et al. J Bacteriol, 2009 Oct. PMID 19633077, Free PMC Article
  2. Deletion analysis of the Escherichia coli ara PC and PBAD promoters. Dunn TM, et al. J Mol Biol, 1984 Nov 25. PMID 6392566
  3. Physical map location of the asc (formerly sac) operon of Escherichia coli K-12. Hall BG, et al. J Bacteriol, 1991 Sep. PMID 1885507, Free PMC Article
  4. A fourth Escherichia coli gene system with the potential to evolve beta-glucoside utilization. Parker LL, et al. Genetics, 1988 Jul. PMID 3042507, Free PMC Article
  5. Nucleotide sequence, function, activation, and evolution of the cryptic asc operon of Escherichia coli K12. Hall BG, et al. Mol Biol Evol, 1992 Jul. PMID 1630307

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional repressor AscG

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2838254..2839264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417194.2 DNA-binding transcriptional repressor AscG

    See identical proteins and their annotated locations for NP_417194.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7LEC5
    Conserved Domains (2) summary
    smart00354
    Location:2 → 69
    HTH_LACI; helix_turn _helix lactose operon repressor
    cd06270
    Location:61 → 329
    PBP1_GalS-like; ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism
Nucleotide Protein
Heading Accession and Version

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