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hyfD hydrogenase 4 component D [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947290, updated on 6-May-2021

Summary

Gene symbol
hyfD
Gene description
hydrogenase 4 component D
Primary source
ASAP:ABE-0008185
Locus tag
b2484
See related
ECOCYC:G7301
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2480
Summary
On the basis of sequence similarity to hycBCDEFG, which encodes hydrogenase 3, the ten-gene cluster hyfABCDEFGHIJ was presumed to encode a hydrogenase that interacts with formate dehydrogenase (FdhF) to produce an active formate hydrogenlyase complex. [More information is available at EcoCyc: G7301].
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Genomic context

Sequence:
NC_000913.3 (2604811..2606250)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase 4 component A Neighboring gene hydrogenase 4 component B Neighboring gene hydrogenase 4 component C Neighboring gene hydrogenase 4 component E Neighboring gene hydrogenase 4 component F Neighboring gene hydrogenase 4 catalytic subunit HyfG

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables NADH dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in electron transport coupled proton transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2604811..2606250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416979.1 hydrogenase 4 component D [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416979.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P77416
    Conserved Domains (1) summary
    PRK06525
    Location:2479
    PRK06525; hydrogenase 4 subunit D; Validated
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