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wrbA NAD(P)H:quinone oxidoreductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947263, updated on 6-May-2021

Summary

Gene symbol
wrbA
Gene description
NAD(P)H:quinone oxidoreductase
Primary source
ASAP:ABE-0003392
Locus tag
b1004
See related
ECOCYC:EG11540
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0995
Summary
WrbA was originally identified as a stationary phase TrpR-binding protein that affected the interaction of TrpR with its operator sites in vitro (Yang, 1993). [More information is available at EcoGene: EG11540]. The purified WrbA protein has NAD(P)H:quinone oxidoreductase activity . [More information is available at EcoCyc: EG11540].
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Genomic context

Sequence:
NC_000913.3 (1067112..1067708, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glucose-1-phosphatase Neighboring gene PF13993 family protein YccJ Neighboring gene stress-induced bacterial acidophilic repeat motifs-containing protein YmdF Neighboring gene pyrimidine:H(+) symporter

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables FMN binding IDA
Inferred from Direct Assay
more info
PubMed 
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 
enables NAD(P)H dehydrogenase (quinone) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables NAD(P)H dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
 
enables NAD(P)H dehydrogenase (quinone) activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within response to oxidative stress IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
NAD(P)H:quinone oxidoreductase
NP_415524.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1067112..1067708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415524.1 NAD(P)H:quinone oxidoreductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415524.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A8G6
    Conserved Domains (1) summary
    PRK03767
    Location:1198
    PRK03767; NAD(P)H:quinone oxidoreductase; Provisional
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