U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

glcA glycolate/lactate:H(+) symporter GlcA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947259, updated on 2-May-2024

Summary

Gene symbol
glcA
Gene description
glycolate/lactate:H(+) symporter GlcA
Primary source
ASAP:ABE-0009763
Locus tag
b2975
See related
ECOCYC:G7542
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2969; yghK
Summary
IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG12995]. YghK, also named GlcA, is a glycolate transporter that belongs to the Lactate Permease Family (LctP) , due to its strong sequence similarity with the L-lactate permease, LldP. [More information is available at EcoCyc: G7542].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3119597..3121279, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene prepilin peptidase Neighboring gene putative lipoprotein YghJ Neighboring gene malate synthase G Neighboring gene putative heme-binding protein GlcG

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables lactate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables solute:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables solute:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in lactate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in lactate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 

General protein information

Preferred Names
glycolate/lactate:H(+) symporter GlcA

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3119597..3121279 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417449.1 glycolate/lactate:H(+) symporter GlcA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417449.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7E8H4, A0AA94SIK6
    Conserved Domains (1) summary
    PRK09695
    Location:1560
    PRK09695; glycolate permease GlcA