U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mazG nucleoside triphosphate pyrophosphohydrolase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947254, updated on 23-Jun-2022

Summary

Gene symbol
mazG
Gene description
nucleoside triphosphate pyrophosphohydrolase
Primary source
ASAP:ABE-0009117
Locus tag
b2781
See related
ECOCYC:EG10572
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2775
Summary
MazG is a nucleoside pyrophosphohydrolase that limits the deleterious effect of the MazF toxin under nutritional stress conditions . [More information is available at EcoCyc: EG10572].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (2909894..2910685, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene enolase Neighboring gene CTP synthetase Neighboring gene endoribonuclease toxin MazF Neighboring gene antitoxin of the MazF-MazE toxin-antitoxin system MazE Neighboring gene GDP/GTP pyrophosphokinase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP diphosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside triphosphate diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleoside triphosphate diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in TTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in UTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cellular response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dATP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dGTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dTTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dUTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
nucleoside triphosphate pyrophosphohydrolase
NP_417261.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2909894..2910685 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417261.1 nucleoside triphosphate pyrophosphohydrolase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417261.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AEY3
    Conserved Domains (1) summary
    PRK09562
    Location:1262
    mazG; nucleoside triphosphate pyrophosphohydrolase; Reviewed