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umpG broad specificity 5'(3')-nucleotidase and polyphosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947211, updated on 8-Dec-2022

Summary

Gene symbol
umpG
Gene description
broad specificity 5'(3')-nucleotidase and polyphosphatase
Primary source
ASAP:ABE-0009008
Locus tag
b2744
See related
ECOCYC:EG11817
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2739; surE; ygbC
Summary
A surE mutation is a specific suppressor of pcm stationary phase survival defects. [More information is available at EcoGene: EG11817]. SurE is a phosphatase with broad substrate specificity. [More information is available at EcoCyc: EG11817].
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Genomic context

Sequence:
NC_000913.3 (2869513..2870274, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase sigma factor RpoS Neighboring gene murein hydrolase activator NlpD Neighboring gene protein-L-isoaspartate O-methyltransferase Neighboring gene tRNA pseudouridine(13) synthase Neighboring gene 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Neighboring gene 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 3'-nucleotidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 3'-nucleotidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 5'-nucleotidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 5'-nucleotidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables exopolyphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables exopolyphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables manganese ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in UMP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within UMP catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 

General protein information

Preferred Names
broad specificity 5'(3')-nucleotidase and polyphosphatase
NP_417224.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2869513..2870274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417224.1 broad specificity 5'(3')-nucleotidase and polyphosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417224.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A840
    Conserved Domains (1) summary
    PRK00346
    Location:1245
    surE; 5'(3')-nucleotidase/polyphosphatase; Provisional