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dgt dGTP triphosphohydrolase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947177, updated on 19-Sep-2024

Summary

Official Symbol
dgt
Official Full Name
dGTP triphosphohydrolase
Primary source
ECOCYC:EG10225
Locus tag
b0160
See related
ASAP:ABE-0000548
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0159; optA
Summary
Deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) is a unique nucleoside triphosphatase in that it hydrolyzes dGTP to deoxyguanosine and inorganic tripolyphosphate. [More information is available at EcoCyc: EG10225].
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Genomic context

Sequence:
NC_000913.3 (179237..180754)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF03458 family protein YadS Neighboring gene vitamin B12 ABC transporter periplasmic binding protein Neighboring gene 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Neighboring gene periplasmic serine endoprotease DegP Neighboring gene DNA-binding transcriptional activator CdaR

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cobalt ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables dGTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables dGTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables dGTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables manganese ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in dGTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in dGTP catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nucleobase-containing small molecule interconversion IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within pyrimidine deoxyribonucleoside salvage IGI
Inferred from Genetic Interaction
more info
PubMed 

General protein information

Preferred Names
dGTP triphosphohydrolase
NP_414702.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    179237..180754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414702.1 dGTP triphosphohydrolase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414702.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7A6RVI6, A0A828PKA7
    Conserved Domains (1) summary
    PRK04926
    Location:1504
    dgt; deoxyguanosinetriphosphate triphosphohydrolase; Provisional