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nrdH glutaredoxin-like protein NrdH [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947161, updated on 11-Apr-2024

Summary

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Gene symbol
nrdH
Gene description
glutaredoxin-like protein NrdH
Primary source
ASAP:ABE-0008802
Locus tag
b2673
See related
ECOCYC:G7401
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2667; ygaN
Summary
Purified NrdH protein was N-terminally sequenced to show the initial Met is not clipped. [More information is available at EcoGene: EG13286]. NrdH is a functional hydrogen donor for ribonucleotide reductase. [More information is available at EcoCyc: G7401].
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Genomic context

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Sequence:
NC_000913.3 (2800723..2800968)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2002 domain-containing protein YgaC Neighboring gene DUF883 domain-containing protein YgaM Neighboring gene dimanganese-tyrosyl radical cofactor maintenance flavodoxin NrdI Neighboring gene ribonucleoside-diphosphate reductase 2 subunit alpha Neighboring gene ribonucleoside-diphosphate reductase 2 subunit beta

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression analysis of the nrdHIEF operon from Escherichia coli. Conditions that trigger the transcript level in vivo. Monje-Casas F, et al. J Biol Chem, 2001 May 25. PMID 11278973
  2. Characterization of Escherichia coli NrdH. A glutaredoxin-like protein with a thioredoxin-like activity profile. Jordan A, et al. J Biol Chem, 1997 Jul 18. PMID 9218434
  3. In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli. Gon S, et al. Antioxid Redox Signal, 2006 May-Jun. PMID 16771665
  4. A method for direct cloning of fur-regulated genes: identification of seven new fur-regulated loci in Escherichia coli. Vassinova N, et al. Microbiology (Reading), 2000 Dec. PMID 11101675
  5. NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. Torrents E, et al. J Bacteriol, 2007 Jul. PMID 17496099, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables electron transfer activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell redox homeostasis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutaredoxin-like protein NrdH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2800723..2800968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417159.1 glutaredoxin-like protein NrdH [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417159.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7L5VB36
    Conserved Domains (1) summary
    PRK10329
    Location:1 → 81
    PRK10329; glutaredoxin-like protein NrdH
Nucleotide Protein
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