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proW glycine betaine ABC transporter membrane subunit ProW [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947145, updated on 6-May-2021

Summary

Gene symbol
proW
Gene description
glycine betaine ABC transporter membrane subunit ProW
Primary source
ASAP:ABE-0008816
Locus tag
b2678
See related
ECOCYC:EG10772
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2672; osrA; proU
Summary
ProVWX, the high-affinity transport system for the osmoprotectant glycine betaine, is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10772].
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Genomic context

Sequence:
NC_000913.3 (2806010..2807074)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene dimanganese-tyrosyl radical cofactor maintenance flavodoxin NrdI Neighboring gene ribonucleoside-diphosphate reductase 2 subunit alpha Neighboring gene ribonucleoside-diphosphate reductase 2 subunit beta Neighboring gene glycine betaine ABC transporter ATP binding subunit ProV Neighboring gene glycine betaine ABC transporter periplasmic binding protein ProX Neighboring gene pseudo

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables amine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables amine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables carnitine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within amine transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in carnitine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in choline transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycine betaine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within glycine betaine transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within glycine betaine transport TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within hyperosmotic response IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within hyperosmotic response IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ATP-binding cassette (ABC) transporter complex ISM
Inferred from Sequence Model
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycine betaine ABC transporter membrane subunit ProW
NP_417164.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2806010..2807074
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417164.1 glycine betaine ABC transporter membrane subunit ProW [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417164.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P14176
    Conserved Domains (1) summary
    PRK10952
    Location:1354
    PRK10952; proline/glycine betaine ABC transporter permease ProW
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