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marC inner membrane protein MarC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947132, updated on 26-Nov-2024

Summary

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Official Symbol
marC
Official Full Name
inner membrane protein MarC
Primary source
ECOCYC:EG11637
Locus tag
b1529
See related
ASAP:ABE-0005106
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1522; ydeB; ydeC
Summary
marC is not regulated by marR and marC mutations and clones do not confer antibiotic phenotypes (McDermott, 2007). marC, ychE and yhgN are paralogs. [More information is available at EcoGene: EG11637]. MarC is an inner membrane protein with six predicted transmembrane domains. [More information is available at EcoCyc: EG11637].
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Genomic context

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Sequence:
NC_000913.3 (1618243..1618908, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YneK Neighboring gene L-arabinose exporter Neighboring gene DNA-binding transcriptional repressor MarR Neighboring gene DNA-binding transcriptional dual regulator MarA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli. Cohen SP, et al. J Bacteriol, 1993 Mar. PMID 8383113, Free PMC Article
  2. Cell-free complements in vivo expression of the E. coli membrane proteome. Savage DF, et al. Protein Sci, 2007 May. PMID 17456747, Free PMC Article
  3. A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. Aiba H, et al. DNA Res, 1996 Dec 31. PMID 9097039
  4. Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis. Drew D, et al. Proc Natl Acad Sci U S A, 2002 Mar 5. PMID 11867724, Free PMC Article
  5. The marC gene of Escherichia coli is not involved in multiple antibiotic resistance. McDermott PF, et al. Antimicrob Agents Chemother, 2008 Jan. PMID 17954692, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. finding show that MarC gene is not involved in multiple antibiotic resistance.
    Title: The marC gene of Escherichia coli is not involved in multiple antibiotic resistance.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
inner membrane protein MarC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1618243..1618908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416046.1 inner membrane protein MarC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416046.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2H4U062, A0A376S8B6
    Conserved Domains (1) summary
    PRK10995
    Location:1 → 221
    PRK10995; MarC family NAAT transporter
Nucleotide Protein
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