U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

aroF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947084, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
aroF
Primary source
ECOCYC:EG10078
Locus tag
b2601
See related
ASAP:ABE-0008549
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2598
Summary
aroF and tyrA encoding the bifunctional chorismate mutase prephenate dehydrogenase form the tyrosine operon. [More information is available at EcoCyc: EG10078].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (2740080..2741150, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene fused chorismate mutase/prephenate dehydratase Neighboring gene fused chorismate mutase/prephenate dehydrogenase Neighboring gene DUF2799 domain-containing lipoprotein YfiL Neighboring gene DUF4154 domain-containing protein YfiR Neighboring gene diguanylate cyclase DgcN

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Stereospecific deuteration of 2-deoxyerythrose 4-phosphate using 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Williamson RM, et al. Bioorg Med Chem Lett, 2005 May 2. PMID 15837321
  2. Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains. Gerigk M, et al. Biotechnol Bioeng, 2002 Dec 30. PMID 12402320
  3. Characterization of a new feedback-resistant 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroF of Escherichia coli. Jossek R, et al. FEMS Microbiol Lett, 2001 Aug 7. PMID 11506923
  4. Overexpression, purification, and characterization of tyrosine-sensitive 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase from Escherichia coli. Ramilo CA, et al. Protein Expr Purif, 1997 Mar. PMID 9056491
  5. Regulation of aromatic amino acid biosynthesis in Escherichia coli K-12: control of the aroF-tyrA operon in the absence of repression control. Camakaris H, et al. J Bacteriol, 1980 Aug. PMID 6782075, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-deoxy-7-phosphoheptulonate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-deoxy-7-phosphoheptulonate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 3-deoxy-7-phosphoheptulonate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid family biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in aromatic amino acid family biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within aromatic amino acid family biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chorismate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive
NP_417092.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2740080..2741150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417092.1 3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417092.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7K0K4
    Conserved Domains (1) summary
    PRK12755
    Location:1 → 353
    PRK12755; phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.