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uxuA D-mannonate dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947082, updated on 9-Mar-2023

Summary

Gene symbol
uxuA
Gene description
D-mannonate dehydratase
Primary source
ASAP:ABE-0014173
Locus tag
b4322
See related
ECOCYC:EG11066
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4313
Summary
UxuR regulon. [More information is available at EcoGene: EG11066]. Mannonate dehydratase catalyzes the final reaction of the glucuronate branch of the hexuronate degradation pathway . [More information is available at EcoCyc: EG11066].
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Genomic context

Sequence:
NC_000913.3 (4551636..4552820)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene type 1 fimbriae D-mannose specific adhesin Neighboring gene fructuronate transporter Neighboring gene D-mannonate oxidoreductase Neighboring gene DNA-binding transcriptional repressor UxuR

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables manganese ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables manganese ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mannonate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mannonate dehydratase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables mannonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannonate dehydratase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in D-glucuronate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within D-glucuronate catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in glucuronate catabolic process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
D-mannonate dehydratase
NP_418742.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4551636..4552820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418742.1 D-mannonate dehydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418742.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P24215
    Conserved Domains (1) summary
    TIGR00695
    Location:1394
    uxuA; mannonate dehydratase