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pheL [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947080, updated on 11-Sep-2024

Summary

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Official Symbol
pheL
Primary source
ECOCYC:EG11271
Locus tag
b2598
See related
ASAP:ABE-0008543
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2595; pheAE
Summary
pheL includes a sequence that increases the frequency of ribosomal frameshifting. [More information is available at EcoCyc: EG11271].
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Genomic context

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Sequence:
NC_000913.3 (2737599..2737646)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane protein assembly factor BamD Neighboring gene ribosome-associated inhibitor A Neighboring gene ncRNA Neighboring gene fused chorismate mutase/prephenate dehydratase Neighboring gene fused chorismate mutase/prephenate dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two groups of phenylalanine biosynthetic operon leader peptides genes: a high level of apparently incidental frameshifting in decoding Escherichia coli pheL. Gurvich OL, et al. Nucleic Acids Res, 2011 Apr. PMID 21177642, Free PMC Article
  2. Nucleotide sequence of the leader region of the phenylalanine operon of Escherichia coli. Zurawski G, et al. Proc Natl Acad Sci U S A, 1978 Sep. PMID 360214, Free PMC Article
  3. pheAo mutants of Escherichia coli have a defective pheA attenuator. Gavini N, et al. J Biol Chem, 1990 Dec 15. PMID 2254312
  4. Nucleotide sequence and transcription of the phenylalanine and tyrosine operons of Escherichia coli K12. Hudson GS, et al. J Mol Biol, 1984 Dec 25. PMID 6396419
  5. Sequences that direct significant levels of frameshifting are frequent in coding regions of Escherichia coli. Gurvich OL, et al. EMBO J, 2003 Nov 3. PMID 14592990, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Characterization of sequence features in pheL that are responsible for frameshifting.
    Title: Two groups of phenylalanine biosynthetic operon leader peptides genes: a high level of apparently incidental frameshifting in decoding Escherichia coli pheL.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
phe operon leader peptide

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2737599..2737646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417089.1 phe operon leader peptide [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417089.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AD72
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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