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yciH putative translation factor [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947058, updated on 20-Feb-2025

Summary

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Official Symbol
yciH
Official Full Name
putative translation factor
Primary source
ECOCYC:EG11128
Locus tag
b1282
See related
ASAP:ABE-0004307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1277
Summary
YciH binds 30S weakly and does not promote disassociation of subunits. [More information is available at EcoGene: EG11128]. YciH has similarity to eIF1, a eukaryotic translation initiation factor which is functionally equivalent to the eubacterial IF3, with the exception of the proofreading function of the IF3 C-terminal domain . [More information is available at EcoCyc: EG11128].
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Genomic context

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Sequence:
NC_000913.3 (1342658..1342984)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide assembly protein A Neighboring gene lipopolysaccharide assembly protein B Neighboring gene orotidine-5'-phosphate decarboxylase Neighboring gene osmotically-inducible lipoprotein OsmB Neighboring gene DNA-binding transcriptional dual regulator YciT

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH. Lomakin IB, et al. EMBO J, 2006 Jan 11. PMID 16362046, Free PMC Article
  2. Nucleotide sequence and characterization of the pyrF operon of Escherichia coli K12. Turnbough CL Jr, et al. J Biol Chem, 1987 Jul 25. PMID 2956254
  3. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Nonaka G, et al. Genes Dev, 2006 Jul 1. PMID 16818608, Free PMC Article
  4. A phylogenetic approach to target selection for structural genomics: solution structure of YciH. Cort JR, et al. Nucleic Acids Res, 1999 Oct 15. PMID 10497266, Free PMC Article
  5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ribosomal small subunit binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translation reinitiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative translation factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1342658..1342984
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415798.2 putative translation factor [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415798.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AQ49
    Conserved Domains (1) summary
    PRK09019
    Location:1 → 108
    PRK09019; stress response translation initiation inhibitor YciH
Nucleotide Protein
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