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nadB L-aspartate oxidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947049, updated on 6-May-2021

Summary

Gene symbol
nadB
Gene description
L-aspartate oxidase
Primary source
ASAP:ABE-0008471
Locus tag
b2574
See related
ECOCYC:EG10631
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2572; nic; nicB
Summary
L-aspartate oxidase (NadB) is the first enzyme in the de novo NAD biosynthesis pathway, catalyzing the FAD-dependent oxidation of L-aspartate to iminoaspartate . [More information is available at EcoCyc: EG10631].
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Genomic context

Sequence:
NC_000913.3 (2710420..2712042)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene anti-sigma factor stabilizing protein RseB Neighboring gene anti-sigma-E factor RseA Neighboring gene RNA polymerase sigma E factor Neighboring gene rpoE leader peptide Neighboring gene tRNA m(6)A37 methyltransferase Neighboring gene ATP-dependent RNA helicase SrmB Neighboring gene putative LysR-type DNA-binding transcriptional regulator YfiE

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables L-aspartate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables L-aspartate oxidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables L-aspartate oxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables L-aspartate oxidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables L-aspartate:fumarate oxidoreductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables L-aspartate:fumarate oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
L-aspartate oxidase
NP_417069.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2710420..2712042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417069.1 L-aspartate oxidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417069.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P10902
    Conserved Domains (1) summary
    PRK09077
    Location:1537
    PRK09077; L-aspartate oxidase; Provisional
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