purL phosphoribosylformylglycinamide synthetase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: purL
Official Full Name: phosphoribosylformylglycinamide synthetase
Primary source: ECOCYC:EG10797
Locus tag: b2557
See related: ASAP:ABE-0008412
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK2555; purI
Summary: Genetic complementation tests showed that the coli purL gene was divided into three domains. [More information is available at EcoCyc: EG10797].
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

N-terminus verified by Edman degradation on complete protein
Title: Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IDA Inferred from Direct Assay more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IDA Inferred from Direct Assay more info	PubMed
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphoribosylformylglycinamidine synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoribosylformylglycinamidine synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables phosphoribosylformylglycinamidine synthase activity	IEA Inferred from Electronic Annotation more info
enables phosphoribosylformylglycinamidine synthase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within 'de novo' IMP biosynthetic process	IC Inferred by Curator more info	PubMed
involved_in 'de novo' IMP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glutamine metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in glutamine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine nucleotide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

YP_026170.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain