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pgpC phosphatidylglycerophosphatase C [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947026, updated on 26-Mar-2025

Summary

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Official Symbol
pgpC
Official Full Name
phosphatidylglycerophosphatase C
Primary source
ECOCYC:EG11371
Locus tag
b2560
See related
ASAP:ABE-0008421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2558; yfhB
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Genomic context

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Sequence:
NC_000913.3 (2697915..2698550, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoribosylformylglycinamide synthetase Neighboring gene membrane-bound lytic murein transglycosylase F Neighboring gene tRNA adenosine(34) deaminase Neighboring gene putative DNA-binding transcriptional regulator YfhH Neighboring gene putative 4Fe-4S cluster-containing protein YfhL

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity. Dillon DA, et al. J Biol Chem, 1996 Nov 29. PMID 8940025
  2. Multiple genes for membrane-bound phosphatases in Escherichia coli and their action on phospholipid precursors. Icho T, et al. J Bacteriol, 1983 Feb. PMID 6296050, Free PMC Article
  3. Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family. Poulsen LK, et al. Mol Microbiol, 1992 Apr. PMID 1602968
  4. Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. El Ghachi M, et al. J Biol Chem, 2005 May 13. PMID 15778224
  5. Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli. Lu YH, et al. J Biol Chem, 2011 Feb 18. PMID 21148555, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylglycerophosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylglycerophosphatase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within glycerophospholipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphatidylglycerol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylglycerophosphatase C
NP_417055.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2697915..2698550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417055.4 phosphatidylglycerophosphatase C [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417055.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3L5H643
    Conserved Domains (1) summary
    PRK11590
    Location:1 → 211
    PRK11590; hypothetical protein; Provisional
Nucleotide Protein
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