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hmp nitric oxide dioxygenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947018, updated on 9-Mar-2022

Summary

Gene symbol
hmp
Gene description
nitric oxide dioxygenase
Primary source
ASAP:ABE-0008396
Locus tag
b2552
See related
ECOCYC:EG10456
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2549; fsrB; hmpA
Summary
Upregulated by GSNO in defined medium (aerobic) as part of the NsrR regulon. hmp mutants are defective in macrophage survival and swarming motility (Stevanin, 2007). [More information is available at EcoGene: EG10456].
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Genomic context

Sequence:
NC_000913.3 (2685835..2687025)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative DNA-binding transcriptional regulator, NAGC-like Neighboring gene serine hydroxymethyltransferase Neighboring gene nitrogen regulatory protein PII-1 Neighboring gene DNA-binding transcriptional activator GlrR Neighboring gene outer membrane lipoprotein QseG

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables FAD binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables FAD binding IDA
Inferred from Direct Assay
more info
PubMed 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
 
enables fatty acid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables heme binding IDA
Inferred from Direct Assay
more info
PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables hydroperoxide reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nitric oxide dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nitric oxide dioxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nitric oxide dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables nitric oxide dioxygenase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
 
enables oxygen carrier activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular response to nitrosative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in nitric oxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in oxygen transport IEA
Inferred from Electronic Annotation
more info
 
involved_in response to nitrosative stress IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to nitrosative stress IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within response to nitrosative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
nitric oxide dioxygenase
NP_417047.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2685835..2687025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417047.1 nitric oxide dioxygenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417047.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P24232
    Conserved Domains (1) summary
    PRK13289
    Location:1396
    PRK13289; NO-inducible flavohemoprotein