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hda inibitor of reinitiation of DNA replication [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946977, updated on 11-Oct-2018

Summary

Gene symbol
hda
Gene description
inibitor of reinitiation of DNA replication
Primary source
EcoGene:EG14201
Locus tag
b2496
See related
ASAP:ABE-0008217; ECOCYC:G7313
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2492; idaB; yfgE
Summary
hda is a DnaA paralog. [More information is available at EcoGene: EG14201]. IdaB is a member of the AAA chaperone-like family of ATPases that is required for the inhibition of the initiation of DNA synthesis via antagonism of DnaA activity by the DNA polymerase III beta subunit (sliding clamp) . [More information is available at EcoCyc: G7313].

Genomic context

Sequence:
NC_000913.3 (2618075..2618776, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene beta-barrel assembly-enhancing protease Neighboring gene putative oxidoreductase YfgD Neighboring gene hypothetical protein Neighboring gene uracil phosphoribosyltransferase

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
ADP binding IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of DNA-dependent DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of DNA-dependent DNA replication initiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
inibitor of reinitiation of DNA replication

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2618075..2618776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416991.2 inibitor of reinitiation of DNA replication [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416991.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69931
    Conserved Domains (1) summary
    PRK08084
    Location:1233
    PRK08084; DNA replication initiation factor; Provisional
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