U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

bamC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946954, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
bamC
Primary source
ECOCYC:EG10658
Locus tag
b2477
See related
ASAP:ABE-0008161
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dapX; ECK2473; nlpB
Summary
RpoE regulon. [More information is available at EcoGene: EG10658]. NlpB is a putative lipoprotein as determined by sequence analysis. [More information is available at EcoCyc: EG10658].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (2597831..2598865, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YpfJ Neighboring gene phosphoribosylaminoimidazole-succinocarboxamide synthase Neighboring gene 4-hydroxy-tetrahydrodipicolinate synthase Neighboring gene putative transcriptional regulator GcvR Neighboring gene thiol peroxidase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Dynamic association of BAM complex modules includes surface exposure of the lipoprotein BamC. Webb CT, et al. J Mol Biol, 2012 Sep 28. PMID 22683355, Free PMC Article
  2. Crystallographic analysis of the C-terminal domain of the Escherichia coli lipoprotein BamC. Kim KH, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2011 Nov 1. PMID 22102230, Free PMC Article
  3. Structure of the BamC two-domain protein obtained by Rosetta with a limited NMR data set. Warner LR, et al. J Mol Biol, 2011 Aug 5. PMID 21624375, Free PMC Article
  4. Secondary structure and (1)H, (13)C and (15)N backbone resonance assignments of BamC, a component of the outer membrane protein assembly machinery in Escherichia coli. Knowles TJ, et al. Biomol NMR Assign, 2009 Dec. PMID 19888691
  5. Studying assembly of the BAM complex in native membranes by cellular solid-state NMR spectroscopy. Pinto C, et al. J Struct Biol, 2019 Apr 1. PMID 29197585

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate structural variations in the central domain, outer membrane protein BamA (BamA), as well as in the lipoprotein outer membrane protein assembly factor BamC (BamC).
    Title: Studying assembly of the BAM complex in native membranes by cellular solid-state NMR spectroscopy.
  2. crystal structure of the C-terminal domain of E. coli BamC (BamC(C): Ala224-Ser343) refined to 1.5 A resolution in space group H3 is reported. BamC(C) consists of a six-stranded antiparallel beta-sheet, three alpha-helices and one 3(10)-helix
    Title: Crystallographic analysis of the C-terminal domain of the Escherichia coli lipoprotein BamC.
  3. The unstructured N terminus of BamC interacts with the proposed substrate-binding pocket of BamD, suggesting that this region of BamC may play a regulatory role in outer membrane protein biogenesis.
    Title: Crystal structure of β-barrel assembly machinery BamCD protein complex.
  4. The Rosetta calculations showed that BamC forms two well-defined domains connected by an ~18-residue linker, where the relative orientation of the domains was not defined.
    Title: Structure of the BamC two-domain protein obtained by Rosetta with a limited NMR data set.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Gram-negative-bacterium-type cell outer membrane assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in Gram-negative-bacterium-type cell outer membrane assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within Gram-negative-bacterium-type cell outer membrane assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein insertion into membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein insertion into membrane IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Bam protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Bam protein complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
outer membrane protein assembly factor BamC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2597831..2598865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416972.4 outer membrane protein assembly factor BamC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416972.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    C3T0D2
    Conserved Domains (1) summary
    PRK11679
    Location:1 → 344
    PRK11679; outer membrane protein assembly factor BamC
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.