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amiA N-acetylmuramoyl-L-alanine amidase A [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946916, updated on 6-May-2021

Summary

Gene symbol
amiA
Gene description
N-acetylmuramoyl-L-alanine amidase A
Primary source
ASAP:ABE-0008032
Locus tag
b2435
See related
ECOCYC:EG11823
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2430; yfeE
Summary
Verified Tat substrate: [More information is available at EcoGene: EG11823]. Escherichia coli contains three N-acetylmuramyl-L-alanine amidases named AmiA, B, and C involved in cell division by splitting the murein septum. [More information is available at EcoCyc: EG11823].
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Genomic context

Sequence:
NC_000913.3 (2552352..2553221)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1131 domain-containing lipoprotein YfeY Neighboring gene putative inner membrane protein Neighboring gene putative acetyltransferase YpeA Neighboring gene coproporphyrinogen III oxidase Neighboring gene putative AraC-type transcriptional regulator EutR

Bibliography

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables N-acetylmuramoyl-L-alanine amidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables N-acetylmuramoyl-L-alanine amidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables N-acetylmuramoyl-L-alanine amidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within cell wall organization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to antibiotic IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in outer membrane-bounded periplasmic space ISM
Inferred from Sequence Model
more info
PubMed 
located_in periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetylmuramoyl-L-alanine amidase A
NP_416930.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2552352..2553221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416930.1 N-acetylmuramoyl-L-alanine amidase A [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416930.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P36548
    Conserved Domains (1) summary
    PRK10319
    Location:1287
    PRK10319; N-acetylmuramoyl-L-alanine amidase AmiA
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