U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

yfeW penicillin binding protein 4B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946907, updated on 9-Mar-2022

Summary

Gene symbol
yfeW
Gene description
penicillin binding protein 4B
Primary source
ASAP:ABE-0008012
Locus tag
b2430
See related
ECOCYC:G7265
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2425
Summary
A mutation in yfeW(pbp4a) does not affect growth on MurNAc (Jaeger, 2008). yfeW(pbp4a) is probably transcribed as part of the murQP-yfeW operon and from a promoter within murP (Jaeger, 2008). [More information is available at EcoGene: EG14164].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (2548102..2549406)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylmuramic acid 6-phosphate etherase Neighboring gene N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter Neighboring gene porphyrinogen peroxidase Neighboring gene DUF1131 domain-containing lipoprotein YfeY

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables penicillin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intrinsic component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in intrinsic component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
penicillin binding protein 4B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2548102..2549406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416925.2 penicillin binding protein 4B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416925.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P77619
    Conserved Domains (1) summary
    PRK03642
    Location:1432
    PRK03642; putative periplasmic esterase; Provisional