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nupC nucleoside:H(+) symporter NupC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946895, updated on 4-Feb-2024

Summary

Gene symbol
nupC
Gene description
nucleoside:H(+) symporter NupC
Primary source
ASAP:ABE-0007893
Locus tag
b2393
See related
ECOCYC:EG11971
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cru; ECK2388
Summary
CytR regulon. nupC, nupX, and yegT are paralogs. [More information is available at EcoGene: EG11971]. NupC is one of two high-affinity nucleoside transporters in Escherichia coli. [More information is available at EcoCyc: EG11971].
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Genomic context

Sequence:
NC_000913.3 (2513042..2514244)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2502 domain-containing protein YpeC Neighboring gene Mn(2(+))/Fe(2(+)): H(+) symporter MntH Neighboring gene protein YpeD Neighboring gene putative IS186/IS421 transposase Neighboring gene putative c-di-GMP phosphodiesterase PdeA

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cytidine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cytidine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleoside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleoside:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables uridine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables uridine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in cytidine transport IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleoside transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nucleoside transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nucleoside transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nucleoside transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in uridine transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nucleoside:H(+) symporter NupC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2513042..2514244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416894.1 nucleoside:H(+) symporter NupC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416894.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376WY91, A0A779ZD29, A0AA36R5R2
    Conserved Domains (1) summary
    COG1972
    Location:4400
    NupC; Nucleoside permease NupC [Nucleotide transport and metabolism]