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murP N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946894, updated on 30-Jul-2025
Official Symbol
murP
Official Full Name
N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter
Primary source
ECOCYC:G7264
Locus tag
b2429
See related
ASAP:ABE-0008009
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2424; yfeV
Summary
MurP contains only EIIBC domains. [More information is available at EcoGene: EG14163]. MurP contains PTS Enzyme IIBC domains of the N-acetylmuramic acid PTS transporter. [More information is available at EcoCyc: G7264].
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Sequence:
NC_000913.3 (2546673..2548097)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator MurR Neighboring gene N-acetylmuramic acid 6-phosphate etherase Neighboring gene penicillin binding protein 4B Neighboring gene porphyrinogen peroxidase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli. Jaeger T, et al. J Bacteriol, 2008 Oct. PMID 18723630, Free PMC Article
  2. Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid. Dahl U, et al. J Bacteriol, 2004 Apr. PMID 15060041, Free PMC Article
  3. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
  4. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130
  5. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Saier MH Jr, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381841, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-N(PI)-phosphohistidine-sugar phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 
Preferred Names
N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter
NP_416924.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2546673..2548097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416924.1 N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter

    See identical proteins and their annotated locations for NP_416924.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8H9SYC6
    Conserved Domains (1) summary
    PRK09586
    Location:2 → 474
    murP; PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
Nucleotide Protein
Heading Accession and Version

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