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prpE propionyl-CoA synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946891, updated on 19-Sep-2024

Summary

Official Symbol
prpE
Official Full Name
propionyl-CoA synthetase
Primary source
ECOCYC:G6200
Locus tag
b0335
See related
ASAP:ABE-0001154
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0332; yahU
Summary
Crp regulon. [More information is available at EcoGene: EG13604]. Acs appears to be more likely than PrpE to catalyze the first step in the propionate metabolism pathway . [More information is available at EcoCyc: G6200].
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Genomic context

Sequence:
NC_000913.3 (352706..354592)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2-methylcitrate synthase Neighboring gene 2-methylcitrate dehydratase Neighboring gene cytosine transporter Neighboring gene cytosine/isoguanine deaminase Neighboring gene DNA-binding transcriptional dual regulator CynR

Pathways from PubChem

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity, forming carbon-sulfur bonds IEA
Inferred from Electronic Annotation
more info
 
enables propionate-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables propionate-CoA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables propionate-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in propionate catabolic process, 2-methylcitrate cycle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
propionyl-CoA synthetase
NP_414869.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    352706..354592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414869.1 propionyl-CoA synthetase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414869.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7H9SDU9
    Conserved Domains (1) summary
    PRK10524
    Location:1628
    prpE; propionyl-CoA synthetase; Provisional