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pdxK pyridoxine/pyridoxal/pyridoxamine kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946881, updated on 6-Jun-2024

Summary

Gene symbol
pdxK
Gene description
pyridoxine/pyridoxal/pyridoxamine kinase
Primary source
ASAP:ABE-0007973
Locus tag
b2418
See related
ECOCYC:G7259
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2413; pdxL; yfeI
Summary
Involved in the salvage pathway of pyridoxal 5'-phosphate biosynthesis. [More information is available at EcoGene: EG12642]. The subunit structure is unknown. [More information is available at EcoCyc: G7259].
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Genomic context

Sequence:
NC_000913.3 (2536386..2537237, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PTS enzyme I Neighboring gene Enzyme IIA(Glc) Neighboring gene DUF5329 domain-containing protein YfeK Neighboring gene PF05406 family protein YfeS

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables hydroxymethylpyrimidine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables hydroxymethylpyrimidine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables pyridoxal kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in pyridoxal 5'-phosphate salvage IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in pyridoxal 5'-phosphate salvage IEA
Inferred from Electronic Annotation
more info
 
involved_in pyridoxal 5'-phosphate salvage IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in pyridoxal 5'-phosphate salvage IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in thiamine salvage IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in vitamin B6 metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
pyridoxine/pyridoxal/pyridoxamine kinase
NP_416913.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2536386..2537237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416913.1 pyridoxine/pyridoxal/pyridoxamine kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416913.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A828U8D4, A0A836NBT7
    Conserved Domains (1) summary
    PRK08176
    Location:1281
    pdxK; pyridoxine/pyridoxal/pyridoxamine kinase