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evgA DNA-binding transcriptional activator EvgA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946841, updated on 19-Sep-2024

Summary

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Official Symbol
evgA
Official Full Name
DNA-binding transcriptional activator EvgA
Primary source
ECOCYC:EG11609
Locus tag
b2369
See related
ASAP:ABE-0007817
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2365
Summary
EvgAS overexpression induces genes involved in acid resistance and drug resistance. [More information is available at EcoGene: EG11609]. Transcription activator EvgA is a member of the two-component regulatory system EvgS/EvgA. [More information is available at EcoCyc: EG11609].
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Genomic context

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Sequence:
NC_000913.3 (2483755..2484369)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tripartite efflux pump membrane subunit EmrY Neighboring gene tripartite efflux pump membrane fusion protein EmrK Neighboring gene protein EvgL Neighboring gene sensor histidine kinase EvgS Neighboring gene acetyl-CoA:oxalate CoA-transferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier. Bock A, et al. Eur J Biochem, 2002 Jul. PMID 12135487
  2. Specificity of the BvgAS and EvgAS phosphorelay is mediated by the C-terminal HPt domains of the sensor proteins. Perraud AL, et al. Mol Microbiol, 1998 Mar. PMID 9535079
  3. Cloning and sequence analysis of the evgAS genes involved in signal transduction of Escherichia coli K-12. Utsumi R, et al. Nucleic Acids Symp Ser, 1992. PMID 1289796
  4. Newly identified genes involved in the signal transduction of Escherichia coli K-12. Utsumi R, et al. Gene, 1994 Mar 11. PMID 8125343
  5. Introduction to bacterial signal transduction networks. Eguchi Y, et al. Adv Exp Med Biol, 2008. PMID 18792678

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcriptional activator EvgA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2483755..2484369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416870.1 DNA-binding transcriptional activator EvgA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416870.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6D0F5L3
    Conserved Domains (1) summary
    PRK09958
    Location:1 → 204
    PRK09958; acid-sensing system DNA-binding response regulator EvgA
Nucleotide Protein
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