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fecI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946839, updated on 11-Sep-2024

Summary

Official Symbol
fecI
Primary source
ECOCYC:EG10291
Locus tag
b4293
See related
ASAP:ABE-0014072
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4283
Summary
Polyamine modulon. [More information is available at EcoGene: EG10291]. FecI (sigma19) was first described as a protein that regulated the expression of genes involved in the transport of ferric citrate ; later, it was determined as sigma factor based on similarities to a subgroup of sigma70 factors, and it binds to the fec transport gene promoter upstream fecA . [More information is available at EcoCyc: EG10291].
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Genomic context

Sequence:
NC_000913.3 (4517714..4518235, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ferric citrate ABC transporter membrane subunit FecC Neighboring gene ferric citrate ABC transporter periplasmic binding protein Neighboring gene ferric citrate outer membrane transporter Neighboring gene ferric citrate regulator FecR Neighboring gene protein YkiE Neighboring gene IS1 family repressor protein InsA Neighboring gene pseudo

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables bacterial-type RNA polymerase core enzyme binding IDA
Inferred from Direct Assay
more info
PubMed 
enables core promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sigma factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sigma factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables sigma factor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of cytosolic DNA-directed RNA polymerase complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA polymerase sigma factor FecI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4517714..4518235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418713.1 RNA polymerase sigma factor FecI [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418713.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377A4L6
    Conserved Domains (1) summary
    PRK09651
    Location:2173
    PRK09651; RNA polymerase sigma factor FecI; Provisional