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yfdR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946834, updated on 11-Sep-2024

Summary

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Official Symbol
yfdR
Primary source
ECOCYC:G7230
Locus tag
b2361
See related
ASAP:ABE-0007791
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2355
Summary
YfdR is a deoxyribonucleoside 5'-monophosphate phosphatase with a conserved HD domain. [More information is available at EcoCyc: G7230].
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Genomic context

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Sequence:
NC_000913.3 (2474984..2475520)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YfdP Neighboring gene DUF2303 domain-containing protein YfdQ Neighboring gene protein YfdS Neighboring gene protein YfdT Neighboring gene putative uncharacterized protein YpdJ Neighboring gene prophage CPS-53 recombination directionality factor and response regulator inhibitor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Escherichia coli Cryptic Prophage Protein YfdR Binds to DnaA and Initiation of Chromosomal Replication Is Inhibited by Overexpression of the Gene Cluster yfdQ-yfdR-yfdS-yfdT. Noguchi Y, et al. Front Microbiol, 2016. PMID 26973617, Free PMC Article
  2. Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli. Zimmerman MD, et al. J Mol Biol, 2008 Apr 18. PMID 18353368, Free PMC Article
  3. Control and regulation of KplE1 prophage site-specific recombination: a new recombination module analyzed. Panis G, et al. J Biol Chem, 2007 Jul 27. PMID 17545146
  4. Proteome analysis of Escherichia coli using high-performance liquid chromatography and Fourier transform ion cyclotron resonance mass spectrometry. Ihling C, et al. Proteomics, 2005 May. PMID 15852340
  5. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 5'-deoxynucleotidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cobalt ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
5'-deoxynucleotidase
NP_416862.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2474984..2475520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416862.2 5'-deoxynucleotidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416862.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376CR64
    Conserved Domains (1) summary
    COG1896
    Location:1 → 177
    YfbR; 5'-deoxynucleotidase YfbR and related HD superfamily hydrolases [Nucleotide transport and metabolism, General function prediction only]
Nucleotide Protein
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