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fecD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946816, updated on 11-Sep-2024

Summary

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Official Symbol
fecD
Primary source
ECOCYC:EG10289
Locus tag
b4288
See related
ASAP:ABE-0014059
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4278
Summary
Probable false positive lipoprotein prediction, 9 CM TMs predicted, Cys not conserved. [More information is available at EcoGene: EG10289]. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. [More information is available at EcoCyc: EG10289].
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Genomic context

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Sequence:
NC_000913.3 (4511458..4512414, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ferric citrate ABC transporter ATP binding subunit Neighboring gene ferric citrate ABC transporter membrane subunit FecC Neighboring gene ferric citrate ABC transporter periplasmic binding protein Neighboring gene ferric citrate outer membrane transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Docking of the periplasmic FecB binding protein to the FecCD transmembrane proteins in the ferric citrate transport system of Escherichia coli. Braun V, et al. J Bacteriol, 2007 Oct. PMID 17660286, Free PMC Article
  2. Citrate-dependent iron transport system in Escherichia coli K-12. Hussein S, et al. Eur J Biochem, 1981 Jul. PMID 6268411
  3. Ferric citrate transport in Escherichia coli requires outer membrane receptor protein fecA. Wagegg W, et al. J Bacteriol, 1981 Jan. PMID 7007312, Free PMC Article
  4. Genetics of the iron dicitrate transport system of Escherichia coli. Pressler U, et al. J Bacteriol, 1988 Jun. PMID 2836368, Free PMC Article
  5. Transmembrane transcriptional control (surface signalling) of the Escherichia coli Fec type. Braun V, et al. FEMS Microbiol Rev, 2005 Sep. PMID 16102597

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SDS results suggest cross-linking of FecB(E93C) to FecD(R54C) and that FecB(E93) is contained in the region that binds to FecD and FecB(E222) in the region that binds to FecC.
    Title: Docking of the periplasmic FecB binding protein to the FecCD transmembrane proteins in the ferric citrate transport system of Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables iron chelate transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular iron ion homeostasis NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron import into cell NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore-dependent iron import into cell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within siderophore-dependent iron import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ferric citrate ABC transporter membrane subunit FecD
NP_418708.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4511458..4512414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418708.1 ferric citrate ABC transporter membrane subunit FecD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418708.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3MNJ1
    Conserved Domains (1) summary
    PRK09777
    Location:1 → 318
    fecD; Fe(3+) dicitrate ABC transporter permease subunit FecD
Nucleotide Protein
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