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sixA phosphohistidine phosphatase SixA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946815, updated on 26-Mar-2025
Official Symbol
sixA
Official Full Name
phosphohistidine phosphatase SixA
Primary source
ECOCYC:G7211
Locus tag
b2340
See related
ASAP:ABE-0007720
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2334; yfcW
Summary
SixA overexpression also interferes with BarA Hpt function (Ogina, 1998). [More information is available at EcoGene: EG14126]. The sixA gene encodes a phosphohistidine phosphatase that specifically removes the phosphoryl group from the His717 residue of ArcB . [More information is available at EcoCyc: G7211].
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Sequence:
NC_000913.3 (2456327..2456812, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene putative fimbrial protein YfcV Neighboring gene 3-hydroxyacyl-CoA dehydrogenase FadJ Neighboring gene 3-ketoacyl-CoA thiolase FadI Neighboring gene DUF406 domain-containing protein YfcZ

Genomic Sequence:
NC_000913.3
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein histidine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein histidine phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein histidine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
phosphohistidine phosphatase SixA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2456327..2456812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416842.1 phosphohistidine phosphatase SixA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416842.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S0FP52
    Conserved Domains (1) summary
    PRK10848
    Location:1159
    PRK10848; phosphohistidine phosphatase SixA