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pdxB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946785, updated on 11-Sep-2024

Summary

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Official Symbol
pdxB
Primary source
ECOCYC:G0-9461
Locus tag
b2320
See related
ASAP:ABE-0007663
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2314; usg-2
Summary
The subunit structure is not yet known. [More information is available at EcoCyc: G0-9461].
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Genomic context

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Sequence:
NC_000913.3 (2436715..2437851, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA pseudouridine(38-40) synthase Neighboring gene putative semialdehyde dehydrogenase Usg Neighboring gene putative flagella assembly protein Neighboring gene putative transporter YfcJ Neighboring gene 3-oxoacyl-[acyl carrier protein] synthase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple turnovers of the nicotino-enzyme PdxB require α-keto acids as cosubstrates. Rudolph J, et al. Biochemistry, 2010 Nov 2. PMID 20831184, Free PMC Article
  2. The isolation and characterization of three types of vitamin B6 auxotrophs of Escherichia coli K12. Hockney RC, et al. J Gen Microbiol, 1979 Feb. PMID 374678
  3. A new family of 2-hydroxyacid dehydrogenases. Grant GA. Biochem Biophys Res Commun, 1989 Dec 29. PMID 2692566
  4. Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12. Lam HM, et al. J Bacteriol, 1990 Nov. PMID 2121717, Free PMC Article
  5. 4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12. Zhao G, et al. FEMS Microbiol Lett, 1996 Jan 15. PMID 8595869

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4-phosphoerythronate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 4-phosphoerythronate dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 4-phosphoerythronate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables NAD binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' pyridoxal 5'-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within 'de novo' pyridoxal 5'-phosphate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pyridoxine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyridoxine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pyridoxine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
erythronate-4-phosphate dehydrogenase
NP_416823.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2436715..2437851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416823.1 erythronate-4-phosphate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416823.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376J1T8, A0A376S9R4, A0A8S7EDP2
    Conserved Domains (1) summary
    PRK15438
    Location:1 → 378
    PRK15438; erythronate-4-phosphate dehydrogenase PdxB; Provisional
Nucleotide Protein
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