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alpA DNA-binding transcriptional activator AlpA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946758, updated on 27-Aug-2023

Summary

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Gene symbol
alpA
Gene description
DNA-binding transcriptional activator AlpA
Primary source
ASAP:ABE-0008636
Locus tag
b2624
See related
ECOCYC:EG12112
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2620
Summary
AlpA is a transcriptional regulator of intA expression . [More information is available at EcoCyc: EG12112].
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Genomic context

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Sequence:
NC_000913.3 (2758644..2758856)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene integrase IntA Neighboring gene uncharacterized protein YfjH Neighboring gene DUF3987 domain-containing protein YfjI Neighboring gene protein YfjJ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alp, a suppressor of lon protease mutants in Escherichia coli. Trempy JE, et al. J Bacteriol, 1989 Jun. PMID 2656652, Free PMC Article
  2. Excision of a P4-like cryptic prophage leads to Alp protease expression in Escherichia coli. Kirby JE, et al. J Bacteriol, 1994 Apr. PMID 7511583, Free PMC Article
  3. Analysis of the Escherichia coli Alp phenotype: heat shock induction in ssrA mutants. Munavar H, et al. J Bacteriol, 2005 Jul. PMID 15995188, Free PMC Article
  4. Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield. Gill RT, et al. Biotechnol Bioeng, 2001 Jan 5. PMID 11084598
  5. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within single-species biofilm formation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within single-species biofilm formation IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcriptional activator AlpA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2758644..2758856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417113.1 DNA-binding transcriptional activator AlpA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417113.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P33997
    Conserved Domains (1) summary
    COG3311
    Location:1 → 68
    AlpA; Predicted DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons]
Nucleotide Protein
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