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nuoJ NADH:quinone oxidoreductase subunit J [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946756, updated on 19-Nov-2025
Official Symbol
nuoJ
Official Full Name
NADH:quinone oxidoreductase subunit J
Primary source
ECOCYC:EG12090
Locus tag
b2280
See related
ASAP:ABE-0007536
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2274
Summary
NuoJ is part of the inner membrane component of NADH dehydrogenase I . [More information is available at EcoCyc: EG12090].
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Sequence:
NC_000913.3 (2395342..2395896, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NADH:quinone oxidoreductase subunit M Neighboring gene NADH:quinone oxidoreductase subunit L Neighboring gene NADH:quinone oxidoreductase subunit K Neighboring gene NADH:quinone oxidoreductase subunit I Neighboring gene NADH:quinone oxidoreductase subunit H Neighboring gene NADH:quinone oxidoreductase subunit G

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme. Pätsi J, et al. Biochem J, 2008 Jan 1. PMID 17894548
  2. Chemical and NADH-induced, ROS-dependent, cross-linking between subunits of complex I from Escherichia coli and Thermus thermophilus. Berrisford JM, et al. Biochemistry, 2008 Sep 30. PMID 18771280
  3. High affinity cation-binding sites in Complex I from Escherichia coli. Euro L, et al. Biochim Biophys Acta, 2009 Aug. PMID 19261245
  4. Inhibition by capsaicin of NADH-quinone oxidoreductases is correlated with the presence of energy-coupling site 1 in various organisms. Yagi T. Arch Biochem Biophys, 1990 Sep. PMID 2118334
  5. Energy-linked reduction of nicotinamide--adenine dinucleotide in membranes derived from normal and various respiratory-deficient mutant strains of Escherichia coli K12. Poole RK, et al. Biochem J, 1974 Oct. PMID 4156832, Free PMC Article

See all (75) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
contributes_to NADH dehydrogenase (ubiquinone) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables NADH dehydrogenase (ubiquinone) activity IEA
Inferred from Electronic Annotation
more info
  
enables NADH dehydrogenase (ubiquinone) activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
contributes_to NADH dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables quinone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in respiratory electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of NADH dehydrogenase complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex I IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of respiratory chain complex I NAS
Non-traceable Author Statement
more info
 PubMed 
Preferred Names
NADH:quinone oxidoreductase subunit J
NP_416783.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2395342..2395896 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416783.1 NADH:quinone oxidoreductase subunit J

    See identical proteins and their annotated locations for NP_416783.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5B9AH01
    Conserved Domains (1) summary
    PRK06638
    Location:1 → 183
    PRK06638; NADH-quinone oxidoreductase subunit J
Nucleotide Protein
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