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menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946720, updated on 9-Mar-2022

Summary

Gene symbol
menD
Gene description
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Primary source
ASAP:ABE-0007482
Locus tag
b2264
See related
ECOCYC:EG10579
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2258
Summary
Mistakenly thought to be SHCHC synthase (Jiang, 2007). [More information is available at EcoGene: EG10579]. The menD gene product catalyzes the first committed step in the biosynthesis of menaquinone. [More information is available at EcoCyc: EG10579].
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Genomic context

Sequence:
NC_000913.3 (2377589..2379259, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene o-succinylbenzoate--CoA ligase Neighboring gene o-succinylbenzoate synthase Neighboring gene 1,4-dihydroxy-2-naphthoyl-CoA synthase Neighboring gene 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Neighboring gene isochorismate synthase MenF Neighboring gene tail-anchored inner membrane protein ElaB

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
NP_416767.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2377589..2379259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416767.1 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416767.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P17109
    Conserved Domains (1) summary
    PRK07449
    Location:1556
    PRK07449; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Validated