Format

Send to:

Choose Destination

fruK 1-phosphofructokinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946676, updated on 6-May-2021

Summary

Gene symbol
fruK
Gene description
1-phosphofructokinase
Primary source
ASAP:ABE-0007174
Locus tag
b2168
See related
ECOCYC:EG10337
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2161; fpk
Summary
Repressed during biofilm formation. [More information is available at EcoGene: EG10337]. 1-phosphofructokinase is essential for the utilization of fructose as a carbon source. [More information is available at EcoCyc: EG10337].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (2261427..2262365, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudouridine-5'-phosphate glycosidase Neighboring gene putative pseudouridine kinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruA Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruB Neighboring gene sugar exporter SetB Neighboring gene putative metal-chelating domain-containing protein YeiW

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 1-phosphofructokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 1-phosphofructokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 1-phosphofructokinase activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphofructokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within fructose catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
1-phosphofructokinase
NP_416673.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2261427..2262365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416673.1 1-phosphofructokinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416673.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AEW9
    Conserved Domains (1) summary
    PRK09513
    Location:1312
    fruK; 1-phosphofructokinase; Provisional
Support Center