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setB sugar exporter SetB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946673, updated on 4-Feb-2024

Summary

Gene symbol
setB
Gene description
sugar exporter SetB
Primary source
ASAP:ABE-0007184
Locus tag
b2170
See related
ECOCYC:EG12034
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2163; yeiO
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG12034]. SetB is a probable efflux transporter for sugars such as lactose and IPTG. [More information is available at EcoCyc: EG12034].
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Genomic context

Sequence:
NC_000913.3 (2263863..2265044)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 1-phosphofructokinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruB Neighboring gene putative metal-chelating domain-containing protein YeiW Neighboring gene elongation factor P-like protein YeiP Neighboring gene putative oxidoreductase YeiQ

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables carbohydrate:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables carbohydrate:proton symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within carbohydrate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to glucose-phosphate stress IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in glucose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within glucose transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in lactose transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lactose transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2263863..2265044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416675.1 sugar exporter SetB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416675.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AA46LQP0
    Conserved Domains (1) summary
    PRK15011
    Location:1393
    PRK15011; sugar efflux transporter SetB