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yehY [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946660, updated on 24-Aug-2024

Summary

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Official Symbol
yehY
Primary source
ECOCYC:EG12011
Locus tag
b2130
See related
ASAP:ABE-0007038
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2123
Summary
RpoS regulon. [More information is available at EcoGene: EG12011]. YehY is a membrane component of an ABC transporter involved in osmoprotection. [More information is available at EcoCyc: EG12011].
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Genomic context

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Sequence:
NC_000913.3 (2217400..2218557, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter membrane subunit YehW Neighboring gene glycine betaine ABC transporter ATP binding subunit YehX Neighboring gene glycine betaine ABC transporter periplasmic binding protein OsmF Neighboring gene beta-D-glucoside glucohydrolase, periplasmic

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Osmoregulatory systems of Escherichia coli: identification of betaine-carnitine-choline transporter family member BetU and distributions of betU and trkG among pathogenic and nonpathogenic isolates. Ly A, et al. J Bacteriol, 2004 Jan. PMID 14702297, Free PMC Article
  2. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
  3. YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Lang S, et al. Biochemistry, 2015 Sep 22. PMID 26325238
  4. Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. Saurin W, et al. J Mol Evol, 1999 Jan. PMID 9873074
  5. Interaction network containing conserved and essential protein complexes in Escherichia coli. Butland G, et al. Nature, 2005 Feb 3. PMID 15690043

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino-acid betaine transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in glycine betaine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glycine betaine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
glycine betaine ABC transporter membrane subunit YehY

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2217400..2218557 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416634.1 glycine betaine ABC transporter membrane subunit YehY [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416634.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YCV4
    Conserved Domains (1) summary
    COG1174
    Location:150 → 385
    OpuBB; ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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