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yehX glycine betaine ABC transporter ATP binding subunit YehX [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946659, updated on 4-Feb-2026
Official Symbol
yehX
Official Full Name
glycine betaine ABC transporter ATP binding subunit YehX
Primary source
ECOCYC:EG12010
Locus tag
b2129
See related
ASAP:ABE-0007034
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2122
Summary
RpoS regulon. [More information is available at EcoGene: EG12010]. YehX is the ATP-binding component of an ABC transporter involved in osmoprotection. [More information is available at EcoCyc: EG12010].
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Sequence:
NC_000913.3 (2216481..2217407, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter membrane subunit YehW Neighboring gene glycine betaine ABC transporter membrane subunit YehY Neighboring gene glycine betaine ABC transporter periplasmic binding protein OsmF Neighboring gene putative periplasmic glycoside hydrolase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Osmoregulatory systems of Escherichia coli: identification of betaine-carnitine-choline transporter family member BetU and distributions of betU and trkG among pathogenic and nonpathogenic isolates. Ly A, et al. J Bacteriol, 2004 Jan. PMID 14702297, Free PMC Article
  2. Sigma(s)-dependent regulation of yehZYXW, which encodes a putative osmoprotectant ABC transporter of Escherichia coli. Checroun C, et al. FEMS Microbiol Lett, 2004 Jul 15. PMID 15251200
  3. YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Lang S, et al. Biochemistry, 2015 Sep 22. PMID 26325238
  4. The Escherichia coli ATP-binding cassette (ABC) proteins. Linton KJ, et al. Mol Microbiol, 1998 Apr. PMID 9593292
  5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type glycine betaine transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ABC-type glycine betaine transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ABC-type glycine betaine transporter activity RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino-acid betaine transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within glycine betaine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in quaternary ammonium group transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
glycine betaine ABC transporter ATP binding subunit YehX

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2216481..2217407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416633.1 glycine betaine ABC transporter ATP binding subunit YehX

    See identical proteins and their annotated locations for NP_416633.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A403D6D4
    Conserved Domains (1) summary
    COG1125
    Location:1 → 308
    OpuBA; ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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