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gatA galactitol-specific PTS enzyme IIA component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946633, updated on 26-Mar-2025

Summary

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Official Symbol
gatA
Official Full Name
galactitol-specific PTS enzyme IIA component
Primary source
ECOCYC:EG12414
Locus tag
b2094
See related
ASAP:ABE-0006932
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2087
Summary
[More information is available at EcoCyc: EG12414].
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Genomic context

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Sequence:
NC_000913.3 (2174597..2175049, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene galactitol-specific PTS enzyme IIB component Neighboring gene putative tagatose-1,6-bisphosphate aldolase 2 chaperone Neighboring gene tagatose-1,6-bisphosphate aldolase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A mutant inducible for galactitol utilization in Escherichia coli K12. Delidakis CE, et al. J Gen Microbiol, 1982 Mar. PMID 7042910
  2. NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA. Volpon L, et al. Protein Sci, 2006 Oct. PMID 16963640, Free PMC Article
  3. Xylitol and D-arabitol toxicities due to derepressed fructose, galactitol, and sorbitol phosphotransferases of Escherichia coli. Reiner AM. J Bacteriol, 1977 Oct. PMID 334721, Free PMC Article
  4. Genotypic exclusion: a novel relationship between the ribitol-arabitol and galactitol genes of E. coli. Link CD, et al. Mol Gen Genet, 1983. PMID 6343795
  5. Mapping of mglB, the structural gene of the galactose-binding protein of Escherichia coli. Boos W, et al. Mol Gen Genet, 1981. PMID 6278261

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. NMR spectroscopy solution of the three-dimensional structure of the IIB subunit (GatB). An NMR titration was performed to identify the GatA-interacting residues.
    Title: NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-phosphocysteine-galactitol-phosphotransferase system transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in galactitol metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within galactitol transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in galactitol transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of transmembrane transporter complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
galactitol-specific PTS enzyme IIA component
NP_416597.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2174597..2175049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416597.1 galactitol-specific PTS enzyme IIA component [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416597.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X3KA23
    Conserved Domains (1) summary
    PRK09665
    Location:1 → 150
    PRK09665; PTS galactitol transporter subunit IIA
Nucleotide Protein
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