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yeaD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946572, updated on 11-Sep-2024

Summary

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Official Symbol
yeaD
Primary source
ECOCYC:G6966
Locus tag
b1780
See related
ASAP:ABE-0005923
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1778; yzzQ
Summary
Downregulated twofold by GSNO in defined medium (aerobic). otherPDB (S. typhimurium): [More information is available at EcoGene: EG12679]. Sequence similarity suggests that YeaD may contain -barrel structure(s) . [More information is available at EcoCyc: G6966].
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Genomic context

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Sequence:
NC_000913.3 (1863850..1864734)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene methionine sulfoxide reductase B Neighboring gene glyceraldehyde-3-phosphate dehydrogenase A Neighboring gene methylglyoxal reductase YeaE Neighboring gene MltA-interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystallization and preliminary X-ray diffraction analysis of the putative aldose 1-epimerase YeaD from Escherichia coli. You W, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2010 Aug 1. PMID 20693678, Free PMC Article
  2. Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases. Chittori S, et al. Acta Crystallogr D Biol Crystallogr, 2007 Feb. PMID 17242513
  3. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Ericsson UB, et al. Anal Biochem, 2006 Oct 15. PMID 16962548
  4. Transcriptional responses of Escherichia coli to S-nitrosoglutathione under defined chemostat conditions reveal major changes in methionine biosynthesis. Flatley J, et al. J Biol Chem, 2005 Mar 18. PMID 15647275
  5. Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium. Monsieurs P, et al. J Mol Evol, 2005 Apr. PMID 15883881

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Full-length Escherichia coli YeaD with an additional 6xHis tag at the C-terminus was crystallized by the hanging-drop vapour-diffusion method using polyethylene glycol 4000 as a precipitant at 283 K.
    Title: Crystallization and preliminary X-ray diffraction analysis of the putative aldose 1-epimerase YeaD from Escherichia coli.
  2. N-terminus verified by Edman degradation on complete protein
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables glucose-6-phosphate 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucose-6-phosphate 1-epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
putative aldose 1-epimerase YeaD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1863850..1864734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416294.4 putative aldose 1-epimerase YeaD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416294.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N0IQD3
    Conserved Domains (1) summary
    COG0676
    Location:3 → 294
    YeaD; D-hexose-6-phosphate mutarotase [Carbohydrate transport and metabolism]
Nucleotide Protein
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