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murR DNA-binding transcriptional dual regulator MurR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946568, updated on 3-Dec-2024
Official Symbol
murR
Official Full Name
DNA-binding transcriptional dual regulator MurR
Primary source
ECOCYC:G7262
Locus tag
b2427
See related
ASAP:ABE-0008000
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2422; yfeT
Summary
MurR is paralogous to RpiR and has both HTH and SIS phosphosugar binding domains. [More information is available at EcoGene: EG14161].
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Sequence:
NC_000913.3 (2544752..2545609, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sulfate/thiosulfate ABC transporter inner membrane subunit CysU Neighboring gene thiosulfate/sulfate ABC transporter periplasmic binding protein CysP Neighboring gene oxidoreductase UcpA Neighboring gene N-acetylmuramic acid 6-phosphate etherase Neighboring gene N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Zhang Y, et al. Nucleic Acids Res, 2022 Jun 10. PMID 35640608, Free PMC Article
  2. Two modes of autoregulation of the murR repressor in Escherichia coli. Ishii D, et al. Biosci Biotechnol Biochem, 2009 Nov. PMID 19897902
  3. The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli. Jaeger T, et al. J Bacteriol, 2008 Oct. PMID 18723630, Free PMC Article
  4. The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12. Pérez-Rueda E, et al. Nucleic Acids Res, 2000 Apr 15. PMID 10734204, Free PMC Article
  5. Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea. Pérez-Rueda E, et al. Comput Biol Chem, 2004 Dec. PMID 15556475

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
    Title: Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
  2. MurR represses transcription from the murQ promoter and also interferes with its own transcription.
    Title: The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables carbohydrate derivative binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-acetylmuramic acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate derivative metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of carbohydrate catabolic process IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional dual regulator MurR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2544752..2545609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416922.1 DNA-binding transcriptional dual regulator MurR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416922.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6BQQ6
    Conserved Domains (1) summary
    PRK15482
    Location:1 → 285
    PRK15482; HTH-type transcriptional regulator MurR
Nucleotide Protein
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