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cynT [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946548, updated on 24-Aug-2024

Summary

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Official Symbol
cynT
Primary source
ASAP:ABE-0001171
Locus tag
b0339
See related
ECOCYC:EG10176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0336
Summary
Escherichia coli encodes two carbonic anhydrases, Can and CynT. cynT is encoded in an operon with cynS, the gene encoding cyanase, and its expression is inducible by cyanate . [More information is available at EcoCyc: EG10176].
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Genomic context

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Sequence:
NC_000913.3 (358799..359458)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cytosine transporter Neighboring gene cytosine/isoguanine deaminase Neighboring gene DNA-binding transcriptional dual regulator CynR Neighboring gene cyanase Neighboring gene cyanate transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of bicarbonate/CO2 in the inhibition of Escherichia coli growth by cyanate. Kozliak EI, et al. J Bacteriol, 1995 Jun. PMID 7768821, Free PMC Article
  2. Identification and characterization of a cyanate permease in Escherichia coli K-12. Sung YC, et al. J Bacteriol, 1989 Sep. PMID 2670891, Free PMC Article
  3. Why is carbonic anhydrase essential to Escherichia coli? Merlin C, et al. J Bacteriol, 2003 Nov. PMID 14563877, Free PMC Article
  4. Indispensability of the Escherichia coli carbonic anhydrases YadF and CynT in cell proliferation at a low CO2 partial pressure. Hashimoto M, et al. Biosci Biotechnol Biochem, 2003 Apr. PMID 12784642
  5. Bacterial carbonic anhydrases. Kozliak EI, et al. EXS, 2000. PMID 11268536

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Carbonic anhydrase in Escherichia coli. A product of the cyn operon.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbonate dehydratase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbon utilization IEA
Inferred from Electronic Annotation
more info
  
involved_in cyanate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cyanate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
carbonic anhydrase 1
NP_414873.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    358799..359458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414873.1 carbonic anhydrase 1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414873.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YF78
    Conserved Domains (1) summary
    cd00884
    Location:7 → 192
    beta_CA_cladeB; Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ...
Nucleotide Protein
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