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dacD D-alanyl-D-alanine carboxypeptidase DacD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946518, updated on 9-Mar-2022

Summary

Gene symbol
dacD
Gene description
D-alanyl-D-alanine carboxypeptidase DacD
Primary source
ASAP:ABE-0006680
Locus tag
b2010
See related
ECOCYC:EG11893
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2004; phsE; yeeC
Summary
First 21 aa predicted to be a type I signal peptide. [More information is available at EcoGene: EG11893]. DacD, also called penicillin-binding protein 6b (PBP6b), is a D-alanyl-D-alanine carboxypeptidase and penicillin-binding protein with sequence similarity to DacA (PBP5) and DacC (PBP6) . [More information is available at EcoCyc: EG11893].
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Genomic context

Sequence:
NC_000913.3 (2081381..2082547, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YeeA Neighboring gene DNA gyrase inhibitor Neighboring gene exodeoxyribonuclease I Neighboring gene putative thiosulfate sulfurtransferase

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables beta-lactamase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables carboxypeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxypeptidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables penicillin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type D-Ala-D-Ala carboxypeptidase activity ISM
Inferred from Sequence Model
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
D-alanyl-D-alanine carboxypeptidase DacD
NP_416514.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2081381..2082547 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416514.4 D-alanyl-D-alanine carboxypeptidase DacD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416514.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P33013
    Conserved Domains (1) summary
    PRK11397
    Location:1388
    dacD; serine-type D-Ala-D-Ala carboxypeptidase DacD