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nac DNA-binding transcriptional dual regulator Nac [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946501, updated on 6-Jul-2026
Official Symbol
nac
Official Full Name
DNA-binding transcriptional dual regulator Nac
Primary source
ECOCYC:G7072
Locus tag
b1988
See related
ASAP:ABE-0006594
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1983
Summary
LysR family. [More information is available at EcoGene: EG14265]. Nac, "nitrogen assimilation control," regulates, without a coeffector, genes involved in nitrogen metabolism under nitrogen-limiting conditions . [More information is available at EcoCyc: G7072].
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Sequence:
NC_000913.3 (2061016..2061933, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Asn Neighboring gene DNA-binding transcriptional activator Cbl Neighboring gene tRNA-Asn Neighboring gene L,D-transpeptidase LdtA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The amino-terminal 100 residues of the nitrogen assimilation control protein (NAC) encode all known properties of NAC from Klebsiella aerogenes and Escherichia coli. Muse WB, et al. J Bacteriol, 1999 Feb. PMID 9922258, Free PMC Article
  2. The nac (nitrogen assimilation control) gene from Escherichia coli. Muse WB, et al. J Bacteriol, 1998 Mar. PMID 9495755, Free PMC Article
  3. Nac-mediated repression of the serA promoter of Escherichia coli. Blauwkamp TA, et al. Mol Microbiol, 2002 Jul. PMID 12123449
  4. Transcriptional repression of gdhA in Escherichia coli is mediated by the Nac protein. Camarena L, et al. FEMS Microbiol Lett, 1998 Oct 1. PMID 9785451
  5. Nitrogen regulation of the codBA (cytosine deaminase) operon from Escherichia coli by the nitrogen assimilation control protein, NAC. Muse WB, et al. J Bacteriol, 2003 May. PMID 12700271, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
DNA-binding transcriptional dual regulator Nac

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2061016..2061933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416493.1 DNA-binding transcriptional dual regulator Nac

    See identical proteins and their annotated locations for NP_416493.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0H2V9R2
    Conserved Domains (1) summary
    PRK11233
    Location:1 → 305
    PRK11233; nitrogen assimilation transcriptional regulator; Provisional
Nucleotide Protein
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